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Bipartisan bill in Congress could aid fight against antibiotic resistant superbugs

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Friday, November 15, 2024   

The fight against infections faces an increasing threat: the rise of superbugs resistant to antibiotics.

The issue already impacts nearly three million and kills 35,000 Americans per year. It poses a threat to the effectiveness of antibiotics going forward if the problem is not addressed.

However, Dr. Paul Pottinger, a professor of infectious diseases at the University of Washington, said this is an avoidable disaster. He noted that it's a natural part of evolution.

"Over time, inevitably, microorganisms will become resistant to the antibiotics that we use," he said. "And that means that we need to have a plan. We need something that's going to forward and help us deal with this threat."

Pottinger said Congress is considering a bipartisan piece of legislation that could help address the shortage of drugs to treat resistant diseases. It's known as the Pioneering Antimicrobial Subscriptions To End Upsurging Resistance or PASTEUR Act.

David Hyun, project director of state health solutions for The Pew Charitable Trusts, said one issue leading to antibiotic-resistant drugs is their overuse, which can hasten their obsolescence. Hyun said it can also be hard to address this issue in the traditional pharmaceutical market where revenue is based on the volume of drugs produced. That creates a disincentive for companies to invest in them.

Hyun said that's where the PASTEUR Act comes in.

"It's a subscription payment model," he said, "that essentially delinks the revenue for a pharmaceutical company that has developed and put on market a new antibiotic, delinks their revenue from the volume of sales and provides an upfront payment to the companies purely based on the public health value of the new antibiotic."

Pottinger said there are ways for people to help too, such as getting all the recommended vaccinations.

"If we're vaccinated and we have a lower risk of respiratory infections or skin infections or GI infections, if we have fewer infections in general, it means we're going to need less antibiotics," he said, "and the less antibiotics we consume, the less resistance we're going to generate."

Support for this reporting was provided by The Pew Charitable Trusts.


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